Author/Authors :
Yasushi Kohno، نويسنده , , Katsuya Awano، نويسنده , , Mitsutomo Miyashita، نويسنده , , Shizuyoshi Fujimori، نويسنده , , Kazuhiko Kuriyama، نويسنده , , Yasuhiko Sakoe، نويسنده , , Shinji Kudoh، نويسنده , , Koji Saito، نويسنده , , Eisuke Kojima، نويسنده ,
Abstract :
A study of the modification of N-alkylanthranilic acids to develop novel DMARDs is detailed. 1,2,3,4-Tetrahydroquinoline-8-carboxylic acid derivatives were found to exhibit a therapeutic effect on adjuvant arthritis and a suppressive effect on bone destruction.
