Author/Authors :
Sergio Mantegani، نويسنده , , Enzo Brambilla، نويسنده , , Paolo Cremonesi، نويسنده , , Carla Caccia، نويسنده , , Maria Gioia Fornaretto، نويسنده , , Nicola Carfagna، نويسنده , , Monica Colombo، نويسنده , , Robert A. McArthur، نويسنده , , Mario Varasi، نويسنده ,
Abstract :
A class of (E) and (Z)-3-styrylpiperidine derivatives was prepared as racemates and evaluated for affinity at σ binding sites labeled with [3H]-(+)-SKF-10,047. Some of these compounds exhibited high affinity and selectivity for σ versus D1 and D2 binding sites.
