Title of article
An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran
Author/Authors
Patrice Préville، نويسنده , , John X. He، نويسنده , , Micheline Tarazi، نويسنده , , M. Arshad Siddiqui، نويسنده , , Wayne L. Cody، نويسنده , , Annette M. Doherty، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
1563
To page
1566
Abstract
Inogatran is an effective and selective pseudopeptide inhibitor of thrombin that has been shown to be efficacious in a series of in vitro and in vivo models of thrombosis. Herein, we report an efficient and convergent chemical synthesis of Inogatran that is amenable to the preparation of multiple gram quantities.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788810
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