Synthesis and anti-HIV activity of some new aminoadamantane heterocycles
Author/Authors :
G. Fytas، نويسنده , , G. Stamatiou، نويسنده , , G. B. Foscolos، نويسنده , , A. Kolocouris، نويسنده , , N. Kolocouris، نويسنده , , M. Witvrouw، نويسنده , , C. Pannecouque، نويسنده , , E. De Clercq، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
4
From page :
1887
To page :
1890
Abstract :
A new class of aminoadamantane heterocycles has been synthesized and examined for anti-HIV activity. Three compounds proved to be active against the replication of HIV-1 in MT-4 cells with an EC50 ranging from 3.6 to 75.2 μM. No activity was noted with any of the compounds against HIV-2.
