Title of article
Novel 7-hydroxycoumarin based fluorescent labels
Author/Authors
Maciej Adamczyk، نويسنده , , Michael Cornwell، نويسنده , , Jeff Huff، نويسنده , , Sushil Rege، نويسنده , , Tata Venkata S. Rao، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
1985
To page
1988
Abstract
Five new 7-hydroxy-8-(N-alkylaminomethyl)coumarin labels (6a-e) were prepared from 4-(4-carboxybutyl)-7-hydroxycoumarin (4) in 28–48% yield. Compared to 4-methylumbelliferone (4-MU, 1), the new fluorescent labels exhibited higher emission intensity over a broader pH range. Extinction coefficients, quantum yields and pKa values are also reported for these labels.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788891
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