Title of article
Enantioselective total synthesis and structure determination of the mercapturic acid sulfoxide conjugate
Author/Authors
Shizuo Nakamura، نويسنده , , Kiyoto Goto، نويسنده , , Mitsuyoshi Kondo، نويسنده , , Shinsaku Naito، نويسنده , , Yoshiaki Tsuda، نويسنده , , Kozo Shishido، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
2033
To page
2036
Abstract
A practical and enantioselective total synthesis of the mercapturic acid sulfoxide 4, a metabolite of anti-inflammatory drug DUP 697 1, has been accomplished by employing the substratecontrolled diastereoselective oxidation of the sulfide 7 to the sulfoxide 8 as the key step. This led to the structure determination of 4.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788900
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