Title of article
Oligodeoxyribonucleotide phosphorothioates kill procyclic Trypanosoma brucei brucei: Quantitative determination of their LD50
Author/Authors
Bouzin C.، نويسنده , , Brouckaert S.، نويسنده , , Cottem D.، نويسنده , , Berens C.، نويسنده , , Sonveaux E.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
2071
To page
2076
Abstract
Phosphorothioates kill the procyclic form of T. brucei brucei by a non antisense but sequence dependent effect. The alamar BlueTM method allowed an easy microscale determination of their antiparasitic effect. The LD50 of the sequences tested was in the range of 11–20 μM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788907
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