Title of article :
Oligodeoxyribonucleotide phosphorothioates kill procyclic Trypanosoma brucei brucei: Quantitative determination of their LD50
Author/Authors :
Bouzin C.، نويسنده , , Brouckaert S.، نويسنده , , Cottem D.، نويسنده , , Berens C.، نويسنده , , Sonveaux E.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Abstract :
Phosphorothioates kill the procyclic form of T. brucei brucei by a non antisense but sequence dependent effect. The alamar BlueTM method allowed an easy microscale determination of their antiparasitic effect. The LD50 of the sequences tested was in the range of 11–20 μM.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
