Title of article
Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamides
Author/Authors
Daniel P. Becker، نويسنده , , Roger Nosal، نويسنده , , Clara I. Villamil، نويسنده , , Gary Gullikson، نويسنده , , Chafiq Moummi، نويسنده , , Dai-Chang Yang، نويسنده , , Daniel L. Flynn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
2149
To page
2154
Abstract
A series of meso-amino(methyl)azanoradamantane benzamides has been prepared and evaluated for 5-HT4 agonism activity in the rat tunica muscularis mucosae (TMM) assay. Compound 8i is the most potent 5-HT4 agonist in the series, with an EC50 of 217 nM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788923
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