Synthesis and in vitro cytotoxicity of aminocoumarin platinum(II) complexes
Author/Authors :
George Kokotos، نويسنده , , Vassiliki Theodorou، نويسنده , , Chryssa Tzougraki، نويسنده , , Dieter L. D. Deforce، نويسنده , , Elfreide G. Van den Eeckhout، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
4
From page :
2165
To page :
2168
Abstract :
A number of cis-dichloro[bis(aminocoumarin)]platinum(II) complexes have been synthesized and evaluated for their in vitro cytotoxicity against Caco-2T cells. The complex with 7-amino-4-trifluoromethylcoumarin as ligand has been found to be the most active (IC50 10 μg/ml) in this study.
