Title of article :
Targeting DNA topoisomerase II with podophyllotoxin aza-analogue
Author/Authors :
Akira Iida، نويسنده , , Masahiro Kano، نويسنده , , Yoshihiro Kubota، نويسنده , , Kenji Koga and Harutoshi Takeo، نويسنده , , Kiyoshi Tomioka، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1997
Pages :
2
From page :
2565
To page :
2566
Abstract :
Oxidation of a cytotoxic podophyllotoxin aza-analogue 2 into the quinone 3succeeded in acquiring DNA topoisomerase II inhibitory activity at a concentration of 25 μM due to stabilization of the cleavable complex.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1997
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
789003
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=789003
