Title of article
ATP analogs with non-transferable groups in the γ position as inhibitors of glycerol kinase
Author/Authors
Cory E. Bystrom، نويسنده , , Donald W. Pettigrew، نويسنده , , S. James Remington، نويسنده , , Bruce P. Branchaud، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
2613
To page
2616
Abstract
β,γ-Difluoromethyleneadenosine-5′-triphosphate (AMP-PCF2P, 3) and γ-arsono-β,γ-methylene-adenosine-5′-diphosphate (AMP-PCAs, 4) were synthesized and were found to be competitive inhibitors of glycerol kinase. Commercially available AMP-PCP and AMP-PNP also are competitive inhibitors. The structural similarities and differences of these ATP analogs and their effect on kinase inhibition are discussed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789013
Link To Document