• Title of article

    Deoxyxylothymidine 3′-O-phosphorothioates: Synthesis, stereochemistry and stereocontrolled incorporation into oligothymidylates

  • Author/Authors

    Xian-bin Yang، نويسنده , , Konrad Misiura، نويسنده , , Marek Sochacki، نويسنده , , Wojciech J. Stec and Linda Jen-Jacobson، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    6
  • From page
    2651
  • To page
    2656
  • Abstract
    New reagent, 5′-O-DMT-xylothymidine 3′-O-(2-thio-4,4-spiropentamethylene-1,3,2-oxathiaphospholane) and its separated diastereomers can be used for stereocontrolled incorporation of xylothymidine 3′-O-phosphorothioate of predetermined sense of P-chirality into desired oligonucleotide constructs.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789020