Title of article
Synthesis of (+)- and (−)-2-methylarachidonyl-2′-fluoroethylamide (O-689)
Author/Authors
William J. Ryan، نويسنده , , W. Kenneth Banner، نويسنده , , Peter J. Crocker، نويسنده , , Billy R. Martin، نويسنده , , Raj K. Razdan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
2669
To page
2672
Abstract
The enantiomers of 2-methylarachidonyl-2′-fluoroethylamide, (+)-4a (>98% ee) and (−)-4b (98% ee), were synthesized from methyl arachidonate and were shown to be nonenantioselective in binding to the cannabinoid receptor (CB1) and in the mouse tetrad tests.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789024
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