Title of article
Site-specific incorporation of photoisomerizable azobenzene groups into ribonuclease S
Author/Authors
David Liu، نويسنده , , John Karanicolas، نويسنده , , Catherine Yu، نويسنده , , Zhihua Zhang، نويسنده , , G. Andrew Woolley، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
2677
To page
2680
Abstract
Syntheses of S-peptide analogues bearing phenylazophenylalanine (Pap) residues at positions 4, 8, and 11 are described. Noncovalent reassociation of the Pap-4 and Pap-11 peptides with S-protein reconstitutes ribonuclease activity. Photoisomerization of the Pap-4 peptide is found to modulate the enzyme activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789026
Link To Document