Title of article
Synthesis and pharmacology of the 1′,2′-dimethylheptyl-Δ8-THC isomers: exceptionally potent cannabinoids
Author/Authors
John W. Huffman، نويسنده , , Sammy G. Duncan Jr.، نويسنده , , Jenny L. Wiley، نويسنده , , Billy R. Martin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
2799
To page
2804
Abstract
The four diastereomers of 1′,2′-dimethylheptyl-Δ8-THC (2) have been synthesized. Pharmacology both in vitro and in vivo indicated that all four isomers were very potent cannabinoids. The 1′R,2′S and 1′S,2′R are considerably more potent than the other two isomers, and are among the most potent traditional cannabinoids known.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789048
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