Title of article :
1,4-Bis-(2,3-epoxypropylamino)-9,10-anthracenedione and related compounds as potent antifungal and antimicrobial agents
Author/Authors :
Zev Lidert، نويسنده , , David H. Young، نويسنده , , Margaret M. Bowers-Daines، نويسنده , , Samuel E. Sherba، نويسنده , , Raj J. Mehta، نويسنده , , Barry C. Lange، نويسنده , , Colin Swithenbank، نويسنده , , Hiroshi Kiyokawa، نويسنده , , Mary G. Johnson، نويسنده , , Susan L. Morris-Natschke، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Abstract :
1,4-Bis-(2,3-epoxypropylamino)-9,10-anthracenedione (1) and related derivatives were assayed for antifungal, antimicrobial, and plant growth regulatory activity. Compound 1 was extremely potent against several strains of fungi, bacteria, and algae (MIC <2 ppm) and controlled two types of downy mildew by 90–100% at a dose of 12 ppm.