• Title of article

    Selective inhibition of low affinity IgE receptor (CD23) processing

  • Author/Authors

    Stuart Bailey، نويسنده , , Brian Bolognese، نويسنده , , Derek R. Buckle، نويسنده , , Andrew Faller، نويسنده , , Sally Jackson، نويسنده , , Pearl Louis-Flamberg، نويسنده , , Mark McCord، نويسنده , , Ruth J. Mayer، نويسنده , , Lisa A. Marshall، نويسنده , , David G. Smith، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    6
  • From page
    29
  • To page
    34
  • Abstract
    A series of hydroxamic acids related to the non-selective matrix metalloproteinase inhibitor Batimastat has been prepared, some members of which are potent inhibitors of the processing of the low affinity IgE receptor (CD 23). Increased activity is obtained by appropriate substitution at the α-position, whilst selectivity is gained by use of a P1′ benzyl group in conjunction with a C-terminal primary amide.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789173