Author/Authors :
Yves P. Auberson، نويسنده , , Pierre Acklin، نويسنده , , Hans Allgeier، نويسنده , , Michel Biollaz، نويسنده , , Serge Bischoff، نويسنده , , Silvio Ofner، نويسنده , , Siem J. Veenstra، نويسنده ,
Abstract :
Potent antagonists at the glycine-binding site of NMDA receptors, as well as dual antagonists acting also at AMPA receptors have been identified in a series of 5-arylaminomethylquinoxaline-2,3-diones. A study of the structure-activity relationship of these compounds is reported here.