Title of article
Synthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720
Author/Authors
Masatoshi Kiuchi، نويسنده , , Kunitomo Adachi، نويسنده , , Toshiyuki Kohara، نويسنده , , Koji Teshima، نويسنده , , Yumi Masubuchi، نويسنده , , Tadashi Mishina، نويسنده , , Tetsuro Fujita، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
101
To page
106
Abstract
Desymmerization of symmetric FTY720 by substitution of different alkyl groups for one of the prochiral hydroxymethyl groups was performed. The size of the alkyl groups and the absolute configuration at quaternary carbon were important on immunosuppressive activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789187
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