Author/Authors :
Richard E. Armer، نويسنده , , Christopher J. Dutton، نويسنده , , Brian R. Fenner، نويسنده , , Sean D. W. Greenwood، نويسنده , , Kim T. Hall، نويسنده , , Andrew J. Rudge، نويسنده ,
Abstract :
Carbocyclic analogues of the antibacterial natural product frenolicin B have been synthesised. These analogues were active against parasitic protozoa of the genus Eimeria and represent a new series of anticoccidial agents. The synthesis of simplified analogues helped to define a possible pharmacophore for frenolicin.
