• Title of article

    Alkylation of succinates: Synthesis of Ro 32–3555

  • Author/Authors

    Kim F. McClure، نويسنده , , Matthew Z. Axt، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    143
  • To page
    146
  • Abstract
    A short synthesis, based on a succinate acylation-alkylation-decarboxylation approach, of the clinical compound Ro 32–3555 is reported. The nature of the selectivity in the mono-alkylation of succinates was examined under varying enolization conditions and in the presence of chaotropic additives.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789195

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=789195