• Title of article

    Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5-methoxy-1-indanone dipeptide benzamides

  • Author/Authors

    Robert T. Lum، نويسنده , , Marek G. Nelson، نويسنده , , Alison Joly، نويسنده , , Amy G. Horsma، نويسنده , , Gavin Lee، نويسنده , , Stephanie M. Meyer، نويسنده , , Michael M. Wick، نويسنده , , Steven R. Schow، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    6
  • From page
    209
  • To page
    214
  • Abstract
    Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high selectivity for the chymotrypsin-like activity of the 20S proteasome.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789212