• Title of article

    Inhibition of thermolysin with nitrone-bearing substrate analogs: A new type of thermolysin inhibitors

  • Author/Authors

    Kyung Joo Lee، نويسنده , , Dong H. Kim and Seiichi Shin ، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    323
  • To page
    326
  • Abstract
    Nitrones are utilized as the active site zinc coordinating functionality in the design of inhibitors for thermolysin. This new type of thermolysin inhibitors are as potent as the existing inhibitors bearing a carboxylate or hydroxamate zinc ligating moiety.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789234