Title of article
Anti-malarial activities of acylated bruceolide derivatives
Author/Authors
Nobutoshi Murakami، نويسنده , , Takashi Umezome، نويسنده , , Taifo Mahmud، نويسنده , , Masanori Sugimoto، نويسنده , , Motomasa Kobayashi، نويسنده , , Yusuke Wataya، نويسنده , , Hye Sook Kim، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
459
To page
462
Abstract
Several O-acylated derivatives of bruceolide (2) were synthesized and their anti-malarial activities together with selective toxicities were examined. It was found that 3,15-di-O-acetyl- (3c), 3,15-di-O-propionyl- (3d) and 15-O-propionylbruceolide (3b), as well as bruceine B (3a), exhibited potent anti-malarial activities with high selective toxicities.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789261
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