Title of article
Solid phase synthesis of benzylamine-derived sulfonamide library
Author/Authors
Sang Woong Kim، نويسنده , , Chang Yong Hong، نويسنده , , Koo Lee، نويسنده , , Eun-Ju Lee، نويسنده , , Jong Sung Koh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
735
To page
738
Abstract
Using solid phase synthesis, a library has been constructed of benzylamine-derived sulfonamides which have strong inhibitory activity against the blood coagulant thrombin. The library compounds were obtained in good yield and high purity; four of these thrombin inhibitors showed nanomolar potency (Ki 600-10 nM).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789314
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