Title of article :
Preparation of 9-deoxo-4″-deoxy-6,9-epoxyerythromycin lactams “motilactides”: Potent and orally active prokinetic agents
Author/Authors :
Ramin Faghih، نويسنده , , Hugh N. Nellans، نويسنده , , Paul A. Lartey، نويسنده , , Albert Petersen، نويسنده , , Kennan Marsh، نويسنده , , Youssef L. Bennani، نويسنده , , Jacob J. Plattner، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
A series of new, highly potent and orally active “motilactides”, 9-deoxo-4″-deoxy-6,9-epoxyerythromycin lactams was designed, synthesized, and evaluated for their gastrointestinal motor stimulating activity. These compounds were acid stable and showed good oral efficacy.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters