Novel HIV- protease inhibitors containing β-hydroxyether and -thioether dipeptide isostere surrogates: modification of the P3 ligand
Author/Authors :
Naginbhai M. Patel، نويسنده , , Frank Bennett، نويسنده , , Viyyoor M. Girijavallabhan، نويسنده , , Bimalendu Dasmahapatra، نويسنده , , Nancy Butkiewicz، نويسنده , , Andrea Hart، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
4
From page :
931
To page :
934
Abstract :
Studies involving modifications to the P3 position of previously described HIV-protease inhibitors1 containing β-hydroxyether and thioether dipeptide isostere replacements led to the discovery of pseudopeptides 8o and 8p with improved antiviral activites.
