Author/Authors :
G. K. Cook، نويسنده , , W. J. Hornback، نويسنده , , J. H. McDonald III، نويسنده , , J. E. Munroe، نويسنده , , N. J. Snyder، نويسنده ,
Abstract :
The enhanced stability of the carbacephem nucleus over the corresponding cephalosporin nucleus has allowed the synthesis of 7-arylglycyl-3-trifluoromethyl-carbacephems. These unique carbacephems possess broad spectrum activity and high stability to both plasmid and chromosomally mediated ß-lactamases.