Author/Authors :
Richard T. Harrison، نويسنده , , M. P. G. Korsgaard، نويسنده , , C. J. Swain، نويسنده , , M. A. Cascieri، نويسنده , , S. Sadowski، نويسنده , , G. R. Seabrook، نويسنده ,
Abstract :
High affinity, selective hNK2 or hNK3 ligands can be prepared from the common template 1 in a few simple chemical operations. The hNK3 ligands 3 antagonise the calcium mobilisation caused by activation of hNK3 receptors expressed in CHO cells as measured using fura-2 microspectrofluorimetry.