• Title of article

    High affinity, selective neurokinin 2 and neurokinin 3 receptor antagonists from a common structural template

  • Author/Authors

    Richard T. Harrison، نويسنده , , M. P. G. Korsgaard، نويسنده , , C. J. Swain، نويسنده , , M. A. Cascieri، نويسنده , , S. Sadowski، نويسنده , , G. R. Seabrook، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    6
  • From page
    1343
  • To page
    1348
  • Abstract
    High affinity, selective hNK2 or hNK3 ligands can be prepared from the common template 1 in a few simple chemical operations. The hNK3 ligands 3 antagonise the calcium mobilisation caused by activation of hNK3 receptors expressed in CHO cells as measured using fura-2 microspectrofluorimetry.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789431