Author/Authors :
Roberto Pellicciari، نويسنده , , Gabriele Costantino، نويسنده , , Emiliano Giovagnoni، نويسنده , , Luisa Mattoli، نويسنده , , Isabelle Brabet، نويسنده , , Jean-Philippe Pin، نويسنده ,
Abstract :
The synthesis and the pharmacological evaluation at metabotropic glutamate receptors of S-2-(4′-carboxy-cubyl)glycine (ACUDA, 9) are described. S-2-(4′-Carboxy-cubyl)glycine is a structurally novel group I selective antagonist for mGluR1 subtype.