Title of article
Synthesis and preliminary evaluation of (S)-2-(4′-carboxycubyl)glycine, a new selective mGluR1 antagonist
Author/Authors
Roberto Pellicciari، نويسنده , , Gabriele Costantino، نويسنده , , Emiliano Giovagnoni، نويسنده , , Luisa Mattoli، نويسنده , , Isabelle Brabet، نويسنده , , Jean-Philippe Pin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1569
To page
1574
Abstract
The synthesis and the pharmacological evaluation at metabotropic glutamate receptors of S-2-(4′-carboxy-cubyl)glycine (ACUDA, 9) are described. S-2-(4′-Carboxy-cubyl)glycine is a structurally novel group I selective antagonist for mGluR1 subtype.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789474
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