• Title of article

    Enantioselective synthesis and pharmacology of 11-hydroxy-(1ʹS,2ʹR)-dimethylheptyl-Δ8-THC

  • Author/Authors

    John Liddle، نويسنده , , John W. Huffman، نويسنده , , Jenny L. Wiley، نويسنده , , Billy R. Martin، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    2223
  • To page
    2226
  • Abstract
    An enantioselective synthesis of the (1ʹS,2ʹR)-dimethylheptyl cannabinoid side chain has been developed and employed in the synthesis of 11-hydroxy-(1ʹS,2ʹR)-dimethylheptyl-Δ8-THC (3). Pharmacology, in vivo and in vitro, indicate (3) to be one of the most potent traditional cannabinoids known.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789601