• Title of article

    Synthesis and biological evaluation of two analogues of (S)-α-methyl-3-carboxyphenylalanine

  • Author/Authors

    Dawei Ma، نويسنده , , Zhaochun Ma، نويسنده , , Alan P. Kozikowski، نويسنده , , Sergey Pshenichkin، نويسنده , , Jarda T. Wroblewski، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    4
  • From page
    2447
  • To page
    2450
  • Abstract
    Two analogues 2, 3 of (S)-α-methyl-3-carboxylphenylalanine 1 were synthesized to test their activity for metabotropic glutamate receptors (mGluRs). Both compounds 2 and 3 were inactive as antagonist for mGluRs, but 2 showed weak agonistic activity for GluR6 in contrast to that reported by Kemp and co-workers.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789643