Exploration of β-turn scaffolding motifs as components of sialyl LeX mimetics and their relevance to P-selectin
Author/Authors :
Stephen Hanessian، نويسنده , , Hoan K. Huynh، نويسنده , , Gurijala V. Reddy، نويسنده , , Grant McNaughton-Smith، نويسنده , , Beat Ernst، نويسنده , , Hartmuth C. Kolb، نويسنده , , John Magnani، نويسنده , , Charla Sweeley، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
6
From page :
2803
To page :
2808
Abstract :
Monocyclic and bicyclic lactam units representing β-turn surrogates were incorporated into a sialyl LeX structure by replacement of the natural sugar components. Low micromolar activity was found in a new P-selectin binding assay.
