Title of article
Rational design of a new series of mixed anti-HIV pronucleotides
Author/Authors
Nathalie Schlienger، نويسنده , , Thierry Beltran، نويسنده , , Christian Perigaud، نويسنده , , Isabelle Lefebvre، نويسنده , , Alain Pompon، نويسنده , , Anne-Marie Aubertin، نويسنده , , Gilles Gosselin، نويسنده , , Jean-Louis Imbach، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
3003
To page
3006
Abstract
MonoSATE aryl phosphotriesters of AZT are able to deliver intracellularly the corresponding 5′-mononucleotide. This process requires activation by an esterase followed by a phosphodiesterase. This finding opens the way to the design of new pronucleotide series.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789748
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