Title of article
Potent inhibitors of the MAP kinase p38
Author/Authors
James R. Henry، نويسنده , , Kenneth C. Rupert، نويسنده , , John H. Dodd، نويسنده , , Ignatius J. Turchi، نويسنده , , Scott A. Wadsworth، نويسنده , , Druie E. Cavender، نويسنده , , Peter H. Schafer، نويسنده , , John J. Siekierka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
3335
To page
3340
Abstract
The MAP kinase p38 plays a key role in the biosynthesis of the inflammatory cytokines TNF-α and IL-1. We have developed a novel series of potent p38 inhibitors that could lead to new methods of treatment for inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789814
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