Title of article
Phenylpiperazine derivatives with strong affinity for 5HT1A, D2A and D3 receptors
Author/Authors
Carmen Ter?n، نويسنده , , Lourdes Santana، نويسنده , , Eugenio Uriarte، نويسنده , , Yagamare Fall، نويسنده , , Lena Unelius، نويسنده , , Bo-Ragnar Tolf، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
3567
To page
3570
Abstract
Four 7-[3-(4-phenyl-1-piperazinyl)propoxy]coumarins were synthesized. The affinities of these compounds for DA (D2A, D3) and 5HT1A receptors were evaluated for their ability to displace [3H]-raclopride and [3H]-8-OH-DPAT respectively from their specific binding sites. The affinities of the target compounds were all in the nanomolar range and followed the order 5-HT1A> D2> D3.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789857
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