Title of article :
Synthesis and evaluation of potent and selective c-GMP phosphodiesterase inhibitors
Author/Authors :
Ginny Dai Ho، نويسنده , , Lisa Silverman، نويسنده , , Ana Bercovici، نويسنده , , Chester Puchalski، نويسنده , , Deen Tulshian، نويسنده , , Yan Xia، نويسنده , , Michael Czarniecki، نويسنده , , Michael Green، نويسنده , , Reneé Cleven، نويسنده , , Hongtao Zhang، نويسنده , , Ahmad Fawzi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Pages :
6
From page :
7
To page :
12
Abstract :
Syntheses and structure-activity relationships (SAR) of cGMP selective phosphodiesterase inhibitors are discussed. Potent and selective inhibitors are produced when the C-2 position of tetracyclic guanine 1 is substituted with alkyl chains containing six carbon atoms.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
1999
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
789883
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=789883
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