Title of article :
2,6,9-trisubstituted purines : Optimization towards highly potent and selective CDK1 inhibitors
Author/Authors :
Patricia Imbach، نويسنده , , Hans-Georg Capraro، نويسنده , , Pascal Furet، نويسنده , , Helmut Mett، نويسنده , , Thomas Meyer، نويسنده , , Jürg Zimmermann، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
Novel 2,6,9-substituted purine derivatives represent a class of potent and selective inhibitors of CDK1/cyclinB. The synthesis, SAR and biological profile of selected compounds are described.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
