Title of article
4-Oxospiro[benzopyran-2,4′-piperidines] as selective α1a-adrenergic receptor antagonists
Author/Authors
Jennie B. Nerenberg، نويسنده , , Jill M. Erb، نويسنده , , Jeffrey M. Bergman، نويسنده , , Stacey OʹMalley، نويسنده , , Raymond S. L. Chang، نويسنده , , Ann L. Scott، نويسنده , , Theodore P. Broten، نويسنده , , Mark G. Bock، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
291
To page
294
Abstract
The 4-oxospiro[benzopyran-2,4′-piperidine] ring system is contained within potent class III antiarrhythmic agents. We highlight how these agents can be chemically transformed into a new class of potent (<1 nM) and selective (>25-fold) α1a-receptor subtype adrenergic tagonists.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789940
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