Title of article :
Manipulation of the C(22)-C(27) region of rapamycin: Stability issues and biological implications
Author/Authors :
Frances C. Nelson، نويسنده , , Shawn J. Stachel، نويسنده , , C. P. Eng، نويسنده , , Suren N. Sehgal، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
A novel series of rapamycin derivatives with modifications in the C(22)-C(27) region has been prepared. These compounds are evaluated for their ability to prevent ring fragmentation while still retaining immunosuppressive capabilities.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
