Author/Authors :
Katsuo Shinozaki، نويسنده , , Hiroki Sato، نويسنده , , Takeo Iwakuma، نويسنده , , Ryuichi Sato، نويسنده , , Tadashi Kurimoto، نويسنده , , Kiyoshi Yoshida، نويسنده ,
Abstract :
A new series of indane derivatives were prepared and evaluated for their thromboxane A2 (TXA2, 1) antagonistic activity. Among these compounds, 24a (Z-335) was found to be a potent TXA2 antagonist in oral administration.