Synthesis of tetrasubstituted bicyclo[3.2.1]octenes as potential inhibitors of influenza virus sialidase
Author/Authors :
Paul S. Jones، نويسنده , , Paul W. Smith، نويسنده , , George W. Hardy، نويسنده , , Peter D. Howes، نويسنده , , Richard J. Upton، نويسنده , , Richard C. Bethell، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Pages :
6
From page :
605
To page :
610
Abstract :
Several racemic bicyclo[3.2.1]octene derivatives have been synthesised and evaluated as inhibitors of influenza virus sialidases. The 5-acetamido-bicyclo[3.2.1]octenol 4 showed modest activity against influenza A and B virus sialidases.
