Author/Authors :
Teruyuki Sakai، نويسنده , , Masahiro Morita، نويسنده , , Naoki Matsunaga، نويسنده , , Kohji Akimoto، نويسنده , , Takashi Yokoyama، نويسنده , , Hiroshi Iijima، نويسنده , , Yasuhiko Koezuka، نويسنده ,
Abstract :
We compared effects of α-galactosylceramide (α-GalCer) and its 3α- or 3β-galactosylated derivatives on the proliferation of murine spleen cells. The 3α-galactosylated α-GalCer showed stongger proliferative response than the parental α-GalCer, but the 3β-galactosylated α-GalCer possessed weaker activity than the α-GalCer. In addition, α-Gal-3-Cer did not show immunostimulatory activity.
