Author/Authors :
James P. Beck، نويسنده , , Matt A. Curry، نويسنده , , Robert J. Chorvat، نويسنده , , Larry W. Fitzgerald، نويسنده , , Paul J. Gilligan، نويسنده , , Robert Zaczek، نويسنده , , George L. Trainor، نويسنده ,
Abstract :
A series of thiazolo[4,5-d]pyrimidine thiones and -ones was prepared and discovered to have good binding affinity to the CRH-R1 receptor, thus showing promise as a new class of potential anxiolytics and/or antidepressants.
