• Title of article

    Isotope edited NMR studies of glycosidases: design and synthesis of a novel glycosidase inhibitor

  • Author/Authors

    Jennifer V. Hines، نويسنده , , Heesun Chang، نويسنده , , Melinda S. Gerdeman، نويسنده , , Dana E. Warn، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    1255
  • To page
    1260
  • Abstract
    N-13C-methyl-deoxynojirimycin was synthesized and used in isotope-edited NMR studies to probe the binding site of an α-glucosidase. Results from this analysis led to the design and preparation of a novel α-glucosidase inhibitor, N-glycyl deoxynojirimycin.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790131