Isotope edited NMR studies of glycosidases: design and synthesis of a novel glycosidase inhibitor

N-13C-methyl-deoxynojirimycin was synthesized and used in isotope-edited NMR studies to probe the binding site of an α-glucosidase. Results from this analysis led to the design and preparation of a novel α-glucosidase inhibitor, N-glycyl deoxynojirimycin.