Title of article :
A highly stereoselective synthesis of plaunotol and its thiourea derivatives as potent antibacterial agents against Helicobacter pylori
Author/Authors :
Hiroshi Kogen، نويسنده , , Keiko Tago، نويسنده , , Masami Arai، نويسنده , , Emiko Minami، نويسنده , , Kayoko Masuda، نويسنده , , Toshiyuki Akiyama، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
Practical and highly stereoselective synthesis of diterpene alcohol, plaunotol (1) and its thiourea derivatives 2a, 3a and 4a, viaZ-selective Wittig reaction between α-acetal ketone 5 and phosphonium salt 6 and their antibacterial activity against Helicobacter pylori are described.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters