Author/Authors :
Ji Suk Lee، نويسنده , , Mi Young Yang، نويسنده , , Hosup Yeo، نويسنده , , Jinwoong Kim، نويسنده , , Hyun Sun Lee، نويسنده , , Jong Seog Ahn، نويسنده ,
Abstract :
Bioactivity-guided fractionation of the CHCl3 extract from hooks of Uncaria rhynchophylla led to the isolation of two triterpene esters, namely uncarinic acids A (1) and B (2). Their structures were established by spectroscopic and chemical methods. These compounds inhibited phospholipase Cγ1 with IC50 values of 35.66 and 44.55 μM, respectively.