• Title of article

    Synthesis of acids as mimetics of 2,3-unsaturated sialic acids for sialidase inhibition

  • Author/Authors

    Pas Florio، نويسنده , , Robin J. Thomson، نويسنده , , Annette Alafaci، نويسنده , , Samia Abo، نويسنده , , Mark von Itzstein، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    4
  • From page
    2065
  • To page
    2068
  • Abstract
    Mimetics of Neu5Ac2en and KDN2en, based on acids, have been synthesised. The Neu5Ac2en mimetic 5 showed inhibition of both bacterial and viral sialidases, with inhibition of the viral sialidase being comparable to that of Neu5Ac2en itself.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790285