Title of article
Synthesis and pharmacological activity of diarylindole derivatives. Cytotoxic agents based on combretastatins
Author/Authors
Manuel Medarde، نويسنده , , Angel C. Ramos، نويسنده , , Esther Caballero، نويسنده , , Rafael Pel?ez-Lamaniéde Clairac، نويسنده , , Jose Luis Lopez Sendon، نويسنده , , Dolores Ga Gr?valos، نويسنده , , Arturo San Feliciano، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2303
To page
2308
Abstract
Taking into account the structure of Combretastatins, we have synthesized and assayed for cytotoxic activity of new indole derivatives. Two aryl groups are maintained in the cis orientation required for activity by means of an indole moiety built up on less active ketoderivatives used as starting materials.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790331
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