Incorrectly folded aromatic polyketides from polyketide reductase deficient mutants
Author/Authors :
Tero Kunnari، نويسنده , , Kristiina Ylihonko، نويسنده , , Anne Hautala، نويسنده , , Karel D. Klika، نويسنده , , Pekka M?nts?l?، نويسنده , , Juha Hakala، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Pages :
4
From page :
2639
To page :
2642
Abstract :
Compounds produced by the polyketide ketoreductase deficient Streptomyces mutants HO61 and P67 are described. The structures of the compounds indicate that ketoreductase activity is required for correct condensation of the polyketide chain in the biosynthesis of aromatic polyketides.